The repercussions of COVID-19 pandemic are still being felt around the world. Frontline medical personnel have borne the brunt of this pandemic, putting their lives on the line while saving others. In scenarios such as this, it is important to ensure their wellbeing, by monitoring their physiological parameters regularly, even continuously. While wrist-worn devices can fulfil this purpose to some extent, they fall short when it comes to delivering clinical-grade data. Sensors integrated in personal protective equipment (PPE) can offer a non-intrusive, continuous mechanism to measure and communicate the physiological parameters of the wearer. They can be in direct contact with the body of the wearer and can be positioned where the different physiological parameters can be accurately measured. At the core of such wearable sensing functionalities lies hybrid printed electronics. Hybrid printed electronics refers to the judicious combination of printed electronics and traditional electronics in such a way that the resulting system inherits the advantages of both. Hybrid printed electronics systems are flexible, stretchable, and even washable, the qualities which are ideal for integration in PPE such as face masks and aprons. In this talk, the possibilities to integrate sensing and communication functionalities in PPE, enabled by hybrid printed electronics, are presented. Medical-grade face mask with integrated electronics is presented as an example of “smart” PPE, which, besides frontline medical personnel, is useful for the general population too in pandemic situations.