Among different types of sensors, piezoelectric sensors are of great interest due to their high sensitivity, long lifetime and fast response time. Some types of piezoelectric sensors have the ability to work in wired and wireless modes. With the advancement in flexible printed electronics, researchers have started to fabricate flexible printed piezoelectric sensors as they are low cost, conformable and have lower frequency of operation than their rigid microfabricated counterpart. However, very few researchers have successfully applied flexible printed electronics technology to develop highly sensitive piezoelectric sensor. This tutorial session will identify the key difficulties to achieve highly sensitive piezoelectric sensor. It will cover conventional materials, processes and design used for flexible printed piezoelectric sensor, their limiting factors and present emerging materials and processes that can overcome those limitations. It will also cover how new circuit topologies can improve the performance of flexible printed piezoelectric sensors. Some of the performance improvement techniques will be presented in the context acoustic wave sensor, a popular type of piezoelectric sensor. The tutorial will present some examples of high performance piezoelectric sensor from from the literature (with some from the author’s laboratory). At the end, the tutorial will allow the attendees to brainstorm on possible ideas (other than the ideas presented in the tutorial) to improve the performance of printed flexible piezoelectric sensors.